- •Cardiac implantable electronic device (CIED) infection and Twiddler’s syndrome are associated with adverse morbidity and mortality outcomes, with key risk factors including patients having undergone multiple/complex procedures.
- •The use of TYRX envelope has been shown in prior studies to reduce the risk of CIED infections as well as Twiddler’s syndrome, although not in the 2 cases we have described.
- •In our cases, the use of TYRX has been associated with the formation of yellow viscous fluid, which in turn could promote hypermobility of the device and leads in the pocket and cause Twiddler’s syndrome.
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Funding Sources: None.
Disclosures: No conflicts of interest to declare for all authors.
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