HRCR Rare Diseases Article Collection
Idiopathic premature ventricular contraction–triggered ventricular fibrillation: Subcutaneous implantable cardioverter-defibrillator (S-ICD) template matched ablation in the absence of inducible clinical premature ventricular contractionIdiopathic ventricular fibrillation is diagnosed in patients who have survived sudden cardiac arrest from ventricular fibrillation (VF) without identifiable structural heart disease.1 It is the main cause of unexplained sudden cardiac death, particularly in young patients under the age of 35.2 An implantable cardioverter-defibrillator (ICD) is usually recommended for the secondary prevention of sudden cardiac death. VF ablation is recommended for clinical VF recurrence and for reducing the number of ICD shocks.
Cardiac sarcoidosis involving the papillary muscle: A case reportSarcoidosis is a granulomatous multisystem disease that is thought to arise from a dysregulated immunological response. A total of 25% of those suffering from sarcoidosis have cardiac involvement on postmortem analysis, but it is clinically apparent in only 5%.1 Isolated cardiac sarcoidosis (CS) has also been described.2 It may manifest as conduction system dysfunction, ventricular arrhythmias, congestive cardiac failure, or sudden cardiac death.3 CS has a predilection for the ventricular myocardium and its clinical presentation may vary from no symptoms to sudden cardiac death.